NBDC Research ID: hum0021.v1



Aims: Identify genes relevant to bipolar disorder

Methods: Whole exome sequence analysis using Illumina HiSeq 2000

Participants/Materials: Three pairs of healthy monozygotic twins

URL: http://www.brain.riken.go.jp/labs/mdmd/index-e.html


Data Set IDType of DataCriteriaRelease Date
JGAS00000000014 NGS (Exome) Controlled Access (Type I) 2015/01/26

*Release Note

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Participants/Materials Three pairs of healthy monozygotic twins
Targets Exome
Target Loci for Capture Methods -
Platform Illumina [HiSeq 2000]
Library Source gDNA extracted from peripheral blood cells
Cell Lines -
Library Construction (kit name) SureSelect Human All Exon 50 Mb Kit (Agilent)
Fragmentation Methods Ultrasonic fragmentation (Covaris S220)
Spot Type Paired-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers) 100 bp
Japanese Genotype-phenotype Archive Data set ID JGAD00000000014
Total Data Volume 118 GB
Comments (Policies)

NBDC policy

This study was supported by “Genome Science”. “Genome Science” is a part of the “Support Programs for Three Fields in Life Sciences (cancer, genome and brain sciences)” established by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) under the Grant-in-Aid for Scientific Research on Innovative Areas.



Principal Investigator: Tadafumi Kato

Affiliation: RIKEN Brain Science Institute

Project / Group Name: Laboratory of Molecular Dynamics of Mental Disorders

URL: http://www.brain.riken.go.jp/labs/mdmd/index-e.html

Funds / Grants (Research Project Number):

NameTitleProject Number

KAKENHI Grant-in-Aid for Challenging Exploratory Research

Search for genetic mutations by next generation sequencing of monozygotic twins discordant for bipolar disorder.




TitleDOIData Set ID


USERS (Controlled-Access Data)

Principal Investigator: Affiliation: Data in Use (Data Set ID)Period of Data Use