NBDC Research ID: hum0175.v1

SUMMARY

Aims: Development of actionable molecular targets and/or biomarkers for prognostication and patient stratification

Methods: Exome analysis by using Illumina HiSeq 2000

Participants/Materials: primary tumor tissues and non-tumor tissues from 69 endometrial carcinoma patients

Data Set ID	Type of Data	Criteria	Release Date
JGAS000174	NGS (Exome)	Controlled Access (Type I)	2019/10/02

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MOLECULAR DATA


Participants/Materials	Endometrial carcinoma (ICD10: C541): 69 cases (tumor tissues: 118 samples, non-tumor tissues: 69 samples)
Targets	Exome
Target Loci for Capture Methods	-
Platform	Illumina [HiSeq 2000]
Library Source	DNAs extracted from tumor or non-tumor tissues
Cell Lines	-
Library Construction (kit name)	SureSelect Human All Exon V4 or V5
Fragmentation Methods	Ultrasonic fragmentation (Covaris)
Spot Type	Paired-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers)	101 bp
Japanese Genotype-phenotype Archive Data set ID	JGAD000254
Total Data Volume	5 TB (fastq)
Comments (Policies)	NBDC policy

Principal Investigator: Nobuhiro Takeshima

Affiliation: The Cancer Institute Hospital of JFCR

Project / Group Name: -

Funds / Grants (Research Project Number):

Name	Title	Project Number
The Vehicle Racing Commemorative Foundation	Exploration of relevant mutations associated with relapsing or refractory ovarian cancer.	5144, 5274, and 5393
KAKENHI Grant-in-Aid for Scientific Research (C)	Genome-wide analyses of endometrial endometrioid carcinoma for early detection and personalized medicine.	26462543
KAKENHI Grant-in-Aid for Scientific Research (C)	Molecular analysis of malignant ascites formation by single-cell RNA-sequencing.	15K06861
KAKENHI Grant-in-Aid for Scientific Research (C)	Identification of the progestin therapy resistance genes in time-course endometrial cancer samples.	17K11308
KAKENHI Grant-in-Aid for Young Scientists (B)	Whole genome sequencing analyses of uterine and ovarian carcinosarcoma.	17K18337
KAKENHI Grant-in-Aid for Scientific Research (C)	Immune microenvironment analyses of uterine and ovarian carcinosarcoma.	18K07338

	Title	DOI	Data Set ID
1
2

Principal Investigator:	Affiliation:	Data in Use (Data Set ID)	Period of Data Use
Masaki Mandai	Kyoto University Faculty of Medicene, department of Gynecology and Obstetrics	JGAD000254	2020/03/13-2025/03/31