NBDC Research ID: hum0137.v1

 

SUMMARY

Aims: To identify susceptibility genes to type 1 diabetes

Methods: NGS (Target Capture)

Participants/Materials: Type 1 diabetes

 

Data Set IDType of DataCriteriaRelease Date
JGAS00000000144 NGS (Target Capture) Controlled Access (Type I) 2018/12/21

*Release Note

* Data users need to apply the Form 2 (Application Form for Using NBDC Human Data) to reach the Controlled Access Data. Learn more

 

MOLECULAR DATA

JGAS00000000144

Participants/Materials Type 1 diabetes (ICD10: E10): 32 cases
Targets Target Capture
Target Loci for Capture Methods

1. chr.12: 53,551,446-53,574,693

2. chr.12: 53,585,106-53,601,000

Platform Thermo Fisher Scientific [Ion Proton]
Library Source DNAs extracted from peripheral blood cells
Cell Lines -
Library Construction (kit name) Amplicon Sequencing
Fragmentation Methods enzymatic shearing
Spot Type Single-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers) 151 bp
Japanese Genotype-phenotype Archive Data set ID JGAD00000000213
Total Data Volume 21 GB (fastq)
Comments (Policies) NBDC policy

 

DATA PROVIDER

Principal Investigator: Hiroshi Ikegami

Affiliation: Department of Endocrinology, Metabolism and Diabetes Kinkdai University Faculty of Medicine

Project / Group Name: Core member for genetic analysis in the committee on type 1 diabetes, Japan Diabetes Society.

Funds / Grants (Research Project Number):

NameTitleProject Number
-

 

PUBLICATIONS

TitleDOIData Set ID
1 A genome-wide association study confirming a strong effect of HLA and identifying variants in CSAD/lnc-ITGB7-1 on chromosome 12q13.13 associated with susceptibility to fulminant type 1 diabetes doi: 10.2337/db18-0314 JGAD00000000213
2

 

USRES (Controlled-Access Data)

Principal Investigator: Affiliation: Data in Use (Data Set ID)Period of Data Use