NBDC Research ID: hum0131.v1
SUMMARY
Aims: Transcriptome analysis for Williams Syndrome (WS)
Methods: RNA-sequencing
Participants/Materials: WS patients and healthy adult individuals
| Dataset ID | Type of Data | Criteria | Release Date |
|---|---|---|---|
| JGAS000132 | NGS (RNA-seq) | Controlled-access (Type I) | 2018/11/20 |
*Data users need to apply an application for Using NBDC Human Data to reach the Controlled-access Data. Learn more
MOLECULAR DATA
| Participants/Materials |
6 WS patients (ICD10: Q253) 8 healthy adults as controls |
| Targets | RNA-seq |
| Target Loci for Capture Methods | - |
| Platform | Thermo Fisher Scientific [Ion Proton] |
| Library Source | RNAs extracted from peripheral blood cells |
| Cell Lines | - |
| Library Construction (kit name) | Ion Total RNA-Seq Kit v2 |
| Fragmentation Methods | Low input RiboMinus Eukaryote System v2 |
| Spot Type | Single-end |
| Read Length (without Barcodes, Adaptors, Primers, and Linkers) | 100 bp |
| Japanese Genotype-phenotype Archive Dataset ID | JGAD000143 |
| Total Data Volume | 54 GB (fastq, txt [Transcripts Per Kilo-base Million: TPM]) |
| Comments (Policies) | NBDC policy & Company User Limit |
DATA PROVIDER
Principal Investigator: Ryo Kimura
Affiliation: Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University
Project / Group Name: -
Funds / Grants (Research Project Number):
| Name | Title | Project Number |
|---|---|---|
| Core Research and Evolutional Science and Technology, Advanced Research & Development Programs for Medical Innovation, Japan Agency for Medical Research and Development (AMED-CREST) | Drug discovery for autism spectrum disorder based on epigenetic research | JP16gm0510008 |
| KAKENHI Grant-in-Aid for Scientific Research (C) | Integrative network analysis of Williams syndrome | 16K09965 |
PUBLICATIONS
| Title | DOI | Dataset ID | |
|---|---|---|---|
| 1 | Integrative network analysis reveals biological pathways associated with Williams syndrome | doi: 10.1111/jcpp.12999 | JGAD000143 |
| 2 |
USRES (Controlled-access Data)
| Principal Investigator | Affiliation | Country/Region | Research Title | Data in Use (Dataset ID) | Period of Data Use |
|---|---|---|---|---|---|
| Michiaki Hamada | Faculty of Science and Engineering, Waseda University | Japan | Construction of RNA-targeted Drug Discovery Database | JGAD000143 | 2022/12/26-2025/03/31 |
