NBDC Research ID: hum0124.v1



Aims: Identification of the genes associated with epidermal growth factor receptor (EGFR)-mutant lung cancer

Methods: exome sequencing

Participants/Materials: lung cancer patients with EGFR-mutants


Data Set IDType of DataCriteriaRelease Date
NGS (Exome) Controlled Access (Type I) 2018/04/06

*Release Note

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Participants/Materials EGFR-mutant lung cancer (ICD10: C34): 3 cases (in 1 family)
Targets Exome
Target Loci for Capture Methods -
Platform Illumina [HiSeq 2000]
Library Source DNAs extracted from peripheral blood cells
Cell Lines -
Library Construction (kit name) SureSelect Target Enrichment System Human All Exon V2
Fragmentation Methods Ultrasonic fragmentation (Covaris)
Spot Type Single-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers) 50 bp
Japanese Genotype-phenotype Archive Data set ID JGAD00000000140
Total Data Volume 9 GB (bam [ref: hg18])
Comments (Policies) NBDC policy



Principal Investigator: Toshiaki Kikuchi

Affiliation: Niigata University Graduate School of Medical and Dental Sciences

Project / Group Name: Department of Respiratory Medicine and Infectious Diseases

Funds / Grants (Research Project Number):

NameTitleProject Number
Project for Development of Innovative Research on Cancer Therapeutics (P-DIRECT) Genetic background on carcinogenic mechanisms of EGFR-mutant lung cancer 15cm0106073h0005
KAKENHI Grant-in-Aid for challenging Exploratory Research Molecular genetics of EGFR-mutant lung cancer 24659399



TitleDOIData Set ID
1 Exome sequencing deciphers a germline MET mutation in familial epidermal growth factor receptor-mutant lung cancer. doi: 10.1111/cas.13233 JGAD00000000140


USRES (Controlled-Access Data)

Principal Investigator: Affiliation: Data in Use (Data Set ID)Period of Data Use