NBDC Research ID: hum0061.v1

 

SUMMARY

Aims: To identify causative genetic aberrations in multiple primary lung cancer

Methods: Whole exome sequencing (Illumina HiSeq 2000)

Participants/Materials: Siblings developed multiple primary lung cancers

 

Data Set IDType of DataCriteriaRelease Date
JGAS00000000057 NGS (Exome) Controlled Access (Type I) 2017/02/20

*Release Note 

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MOLECULAR DATA

JGAS00000000057

Participants/Materials Siblings developed multiple primary lung cancers
Targets Exome
Target Loci for Capture Methods -
Platform Illumina [HiSeq 2000]
Library Source gDNA extracted from peripheral blood cells of siblings developed multiple primary lung cancers
Cell Lines -
Library Construction (kit name) BGI exome sequencing service
Fragmentation Methods BGI exome sequencing service
Spot Type Paired-end
Read Length (without Barcodes, Adaptors, Primers, and Linkers) 90 bp
Japanese Genotype-phenotype Archive Data set ID JGAD00000000057
Total Data Volume

29 GB

  Data files: 8 (fastq)

  Analysis files: 4 (vcf [ref: hg19])

Comments (Policies) NBDC policy

 

DATA PROVIDER

Principal Investigator: Kikuya Kato

Affiliation: Osaka Medical Center for Cancer and Cardiovascular Diseases

Project / Group Name: -

Funds / Grants (Research Project Number):

NameTitleProject Number
KAKENHI Grant-in-Aid for Scientific Research (C) Identification of causative genes for hereditary cancer by genome analyses of familial cancer cases and its application 25430180
The Osaka Community Foundation Searching causative genes of familial or sporadic rare tumors using whole gene sequencing -
The Charitable Trust Osaka Cancer Research Foundation Searching causative genetic aberrations of familial or sporadic rare tumors by genome analyses of patients -
The Osaka Medical Research Foundation for Intractable Diseases Searching causative genes of familial cancers by genome analyses of sibling patients with rare cancer -

 

PUBLICATIONS

TitleDOIData Set ID
1 Homozygous inactivation of CHEK2 is linked to a familial case of multiple primary lung cancer with accompanying cancers in other organs doi: 10.1101/mcs.a001032 JGAD00000000057
2

 

USRES (Controlled-Access Data)

Principal Investigator: Affiliation: Data in Use (Data Set ID)Period of Data Use