NBDC Research ID: hum0059.v1
SUMMARY
Aims: Establishment of novel therapeutic strategy to overcome intractable cancer by molecular profiling of serous ovarian cancer
Methods: Exome analysis by using Illumina HiSeq 2000
Participants/Materials: 148 normal, primary tumor and relapse tumor tissues from 65 ovarian cancer
| Dataset ID | Type of Data | Criteria | Release Date |
|---|---|---|---|
| JGAS000104 | NGS (Exome) | Controlled-access (Type I) | 2018/04/06 |
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MOLECULAR DATA
| Participants/Materials |
ovarian cancer: 65 cases (total: 148 samples) non-tumor tissues: 67 samples tumor tissues: 81 samples |
| Targets | Exome |
| Target Loci for Capture Methods | - |
| Platform | Illumina [Hiseq 2000] |
| Library Source | DNAs extracted from non-tumor, primary tumor, and relapse tumor tissues |
| Cell Lines | - |
| Library Construction (kit name) |
SureSelect Human All Exon V4 + lincRNA SureSelect Human All Exon V5 + lincRNA |
| Fragmentation Methods | Ultrasonic fragmentation (Covaris E220) |
| Spot Type | Paired-end |
| Read Length (without Barcodes, Adaptors, Primers, and Linkers) | 100 bp |
| Japanese Genotype-phenotype Archive Dataset ID | JGAD000109 |
| Total Data Volume | 3 TB (fastq) |
| Comments (Policies) | NBDC policy |
DATA PROVIDER
Principal Investigator: Kazuyoshi Kato
Affiliation: The Cancer Institute Hospital of JFCR
Project / Group Name: -
Funds / Grants (Research Project Number):
| Name | Title | Project Number |
|---|---|---|
| Project for Development of Innovative Research on Cancer Therapeutics (P-DIRECT), Japan Agency for Medical Research and Development (AMED) | Development of the Intractable Cancer Therapies through the New Target Identification by the Molecular Profiling | JP15cm0106061 |
| JSPS KAKENHI |
PUBLICATIONS
| Title | DOI | Dataset ID | |
|---|---|---|---|
| 1 | - |
USRES (Controlled-access Data)
| Principal Investigator | Affiliation | Country/Region | Research Title | Data in Use (Dataset ID) | Period of Data Use |
|---|---|---|---|---|---|
| Masaki Mandai | Kyoto University Faculty of Medicene, department of Gynecology and Obstetrics | Integrated analyses of omics (genomics, transcriptomics, proteomics and metabolomics) associated with clinical variables for developing indivisualizedtreatment in gynecological malignancy | JGAD000109 | 2018/10/04-2025/03/31 | |
| Kouya Shiraishi | Division of Genome Biology, National Cancer Research Institute | Elucidation of immune-system networks between host and tumor based on genomic analysis | JGAD000109 | 2019/08/05-2023/03/31 |
