NBDC Research ID: hum0004.v1

 

SUMMARY

Aims: Molecular epidemiological study of somatic mutation profiles of epidermal growth factor receptor: EGFR mutation-positive lung adenocarcinoma

Methods: Whole Genome Sequence (Illumina [Genome Analyzer IIx])

Participants/Materials: 97 Japanese lung adenocarcinoma patients as tumor-normal pairs.

 

Data Set IDType of DataCriteriaRelease Date
JGAS00000000001 NGS (Exome) Controlled Access (Type I) 2014/07/11

*Release Note

* Data users need to apply the Form 2 (Application Form for Using NBDC Human Data) to reach the Controlled Access Data. Learn more

 

MOLECULAR DATA

JGAS00000000001

Participants/Materials 97 Japanese lung adenocarcinoma patients as tumor-normal pairs
Targets Exome
Target Loci for Captur Methods -
Platforms Illumina [Genome Analyzer IIx]
Library Sources DNAs extracted from adenocarcinoma and non-adenocarcinoma
Cell Lines -
Library Construction (kit name) SureSelect Target Enrichment System
Fragmentation Methods Ultrasonic fragmentation (Covaris)
Spot Type Paired-end reads
Read Length (without Barcodes, Adaptors, Primers, and Linkers) 76 bp x 2
Japan Genotype-Phenotype Archive Data Set ID JGAD00000000001
Total Data Volume
Comments (Policies) NBDC policy & hum0004 policy

 

DATA PROVIDER

Principal Investigator: Koichi Goto

Thoracic Oncology Division, the National Cancer Center Hospital East

Project / Groupe Name: The Exploratory Oncology Research & Clinical Trial Center (the National Cancer Center)

URL: http://epoc.ncc.go.jp/about/staff/tsuchihara.php

Funds / Grants (Research Project Number):

NameTitleProject Number

KAKENHI

Grant-in-Aid for Scientific Research (B)

Searching for kinases related to lung cancerbased on genomic analysis forlung adenocarcinoma 24300345

 

PUBLICATIONS

TitleDOIData Set ID
1 Identification and characterization of cancer mutations in Japanese lung adenocarcinoma without sequencing of normal tissue counterparts. doi: 10.1371/journal.pone.0073484. eCollection 2013. JGAD00000000001
2      

 

USERS (Controlled Access Data)

PIAffiliationData in Use (Data Set ID)Period of Data Use
Youping Deng Department of Complementary and Integrative Medicine, University of Hawai Manoa JGAD00000000001 2018/10/04-2025/07/10